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radiotherapy
 
RIA/IRMA
 
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GUIDELINES TO SET UP A RADIOIMMUNOASSAY (RIA) LABORATORY

 

Introduction:

In recent years, radioisotope techniques are used in medicine for a wide variety of diagnostic procedures. Among the many applications of radioisotopes, Radioimmunoassasy (RIA) has already been established as a versatile and unique procedure. The advantage of this technique is that it does not involve administration of radioisotopes to the patient and so no radiation exposure to the patient. These assays are useful for the clinical evaluation of the concentration levels of vitally important biological ingredients such as hormones, vitamins, steroids, drugs etc. thereby enabling early diagnosis of various diseases and better management of treatment. RIA work involves the handling and use of very small quantities of radioisotopes, usually not exceeding 3.7 MBq of lodine-125 and Tritium (3H). Atomic Energy (Radiation Protection), Rules (2004) promulgated under the Atomic Energy Act, 1962 requires that the user should obtain authorisation from Atomic Energy Regulatory Board (AERB) for handling radioisotopes. Usually, these authorizations are issued subject to the user satisfying the basic safety requirements and adequate trained staff.

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